Centrally Acting Peptides

Front Matter....Pages i-x
Isolation and identification of biologically active peptides....Pages 1-15
Immunohistochemical localization of peptides in the nervous system....Pages 17-35
Are hypothalamic hormones central neurotransmitters?....Pages 37-47
Diffuse neuroendocrine system: peptides common to brain and intestine and their relationship to the APUD concept....Pages 49-57
Electrophysiological analysis of peptide actions in neural tissue....Pages 59-84
Comparative features of enkephalin and neurotensin in the mammalian central nervous system....Pages 85-97
Behavioural effects of hypothalamic peptides....Pages 99-118
Substance P: a historical account....Pages 119-134
Distribution and release of Substance P in the central nervous system....Pages 135-155
Endogenous opioid peptides: historical aspects....Pages 157-159
Physiological and clinical relevance of endorphins....Pages 161-178
Pharmacological and biochemical aspects of the enkephalins....Pages 179-193
Distribution and pharmacology of the enkephalins and related opiate peptides....Pages 195-213
Electrophysiological effects of opiates and opioid peptides....Pages 215-229
Biogenesis and metabolism of opiate active peptides....Pages 231-239
Behavioural effects of neuropeptides related to ß-LPH....Pages 241-251
Back Matter....Pages 253-259