Animal Models of Obesity

Front Matter....Pages i-x
Normal variation in body fat and its inheritance....Pages 1-14
The inheritance of obesity in animal models of obesity....Pages 15-37
The characteristics of genetically obese mutants....Pages 39-64
The husbandry and maintenance of genetic models of obesity....Pages 65-78
The use of animal models in the detection and evaluation of compounds for the treatment of obesity....Pages 79-90
Abnormal function of the endocrine pancreas in genetic and experimentally induced obesity in rodents....Pages 91-106
Adipose tissue in genetically obese rodents....Pages 107-130
Non-genetic models of obesity....Pages 131-140
Energy balance in reversible obesity....Pages 141-151
Lipogenesis and hormone resistance in liver and adipose tissue of genetically obese mice....Pages 153-175
The hypothalamo — pituitary system in obesity....Pages 177-190
Thermoregulation in genetically obese rodents: the relationship to metabolic efficiency....Pages 191-203
Immunity in genetically obese rodents....Pages 205-220
Comparison of genetic models of obesity in animals with obesity in man....Pages 221-235
The clinician’s approach....Pages 237-249
Back Matter....Pages 250-258