Selectivity and Molecular Mechanisms of Toxicity

Front Matter....Pages i-ix
Front Matter....Pages 1-1
Cellular Specific Toxicity in the Lung....Pages 3-26
Organophosphate-induced Delayed Neuropathy: Anomalous Data Lead to Advances in Understanding....Pages 27-58
The Nephrotoxicity of Haloalkane and Haloalkene Glutathione Conjugates....Pages 59-83
Dioxin and Organotin Compounds as Model Immunotoxic Chemicals....Pages 85-102
Front Matter....Pages 103-103
Toxic Lectins and Related Ribosome-inactivating Plant Proteins....Pages 105-124
Mechanisms of Ageing of Organophosphate-inhibited Esterases....Pages 125-152
Mechanisms of Genotoxicity of Chlorinated Aliphatic Hydrocarbons....Pages 153-181
Drugs as Suicide Substrates of Cytochrome P-450....Pages 183-210
Front Matter....Pages 211-211
Parkinsonian Syndrome Caused by 1-Methyl-4-Phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Man and Animals....Pages 213-248
Hexane Neuropathy: Studies in Experimental Animals and Man....Pages 249-263
Toxicology of Impurities in Malathion: Potentiation of Malathion Toxicity and Lung Toxicity Caused by Trialkyl Phosphorothioates....Pages 265-294
Back Matter....Pages 295-302